Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dinoseb. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinoseb SCHEMBL5933875 | 1.00 | TDP1 (0.53) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL8534879 | 0.89 | TDP1 (0.62) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL29365762 | 0.89 | TDP1 (0.62) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL54664 | 0.89 | TDP1 (0.62) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL9949230 | 0.88 | TDP1 (0.61) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL5933971 | 0.88 | TDP1 (0.61) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL29400673 | 0.88 | TDP1 (0.61) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL5933953 | 0.85 | TDP1 (0.53) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL10889997 | 0.84 | TDP1 (0.52) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| Dinoseb SCHEMBL11343942 | 0.83 | GPR35 (0.68) | TDP1GPR35ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |