Dinoseb

Dinoseb

SCHEMBL29400673

CCC(C)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O.N

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.61
GPR35 Q9HC97 6/20 0.53
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
MAPK1 P28482 3/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
TTR P02766 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
RECQL P46063 1/20 0.51
PMP22 Q01453 1/20 0.51
HIF1A Q16665 1/20 0.51
HSD17B10 Q99714 1/20 0.51
GRM8 O00222 1/20 0.44
GRM4 Q14833 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinoseb SCHEMBL5933971 1.00 TDP1 (0.61) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL8534879 0.98 TDP1 (0.62) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL54664 0.98 TDP1 (0.62) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL29365762 0.98 TDP1 (0.62) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL9949230 0.97 TDP1 (0.61) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL11343942 0.92 GPR35 (0.68) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL11790365 0.89 TDP1 (0.57) TDP1GPR35ALDH1A1KMT2AMEN1
SCHEMBL11776456 0.89 TDP1 (0.57) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL5933953 0.88 TDP1 (0.53) TDP1GPR35ALDH1A1KMT2AMEN1
Dinoseb SCHEMBL31734134 0.88 TDP1 (0.53) TDP1GPR35ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP disclosed
US-20250312364-A1 METHODS FOR THE USE OF PSYCHEDELICS TRYP THERAPEUTICS INC. (CA) 2025-10-09 US disclosed
WO-2025052002-A1 METHOD FOR HYDROXYLATION OF BILE ACIDS OR ANALOGUES THEREOF Centrient Pharmaceuticals Netherlands B.V. (NL) 2025-03-13 WO disclosed
US-20240307420-A1 IMPROVED METHODS FOR THE USE OF PSYCHEDELICS TRYP THERAPEUTICS INC. (CA) 2024-09-19 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11931452-B2 Topical compositions containing rofecoxib and methods of making and using the same JF PHARMA TECH LLC (US) 2024-03-19 US disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
EP-4308128-A2 IMPROVED METHODS FOR THE USE OF PSYCHEDELICS Tryp Therapeutics Inc. (CA) 2024-01-24 EP disclosed
EP-2970176-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-10-25 EP disclosed
EP-4045480-A1 PHARMACEUTICAL FORMULATIONS First Wave Bio, Inc. (US) 2022-08-24 EP disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20220105057-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-04-07 US disclosed
US-20220079897-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-03-17 US disclosed
WO-2022051316-A1 FIXED DOSE COMBINATIONS OF CHS-131 AND A SGLT-2 INHIBITOR Coherus Biosciences, Inc. (US) 2022-03-10 WO disclosed
WO-2022051323-A1 FIXED DOSE COMBINATIONS OF CHS-131 AND A PPAR AGONIST Coherus Biosciences, Inc. (US) 2022-03-10 WO disclosed
WO-2022051318-A1 FIXED DOSE COMBINATIONS OF CHS-131 AND A THYROID RECEPTOR BETA AGONIST Coherus Biosciences, Inc. (US) 2022-03-10 WO disclosed
US-11260023-B2 Topical compositions containing rofecoxib and methods of making and using the same BRIORI BIOTECH, LLC (US) 2022-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT TDP1 289/4885GPR35 1908/4885ALDH1A1 960/4885
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 TDP1 2650/4885GPR35 1513/4885ALDH1A1 978/4885
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 TDP1 1443/4885GPR35 535/4885ALDH1A1 2174/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 TDP1 2650/4885GPR35 1513/4885ALDH1A1 978/4885
US-20220079897-A1 METHODS OF TREATMENT ACE2, ACE, SI TDP1 3753/4885GPR35 354/4885ALDH1A1 3977/4885
US-20220105057-A1 METHODS OF TREATMENT ACE2, ACE, SI TDP1 3910/4885GPR35 428/4885ALDH1A1 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.