SCHEMBL31734720

SCHEMBL31734720

CC(C)(C)OC(=O)COCCCCOCCCCOCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.58
PPARA Q07869 2/20 0.46
TDP1 Q9NUW8 1/20 0.43
PPARG P37231 1/20 0.42
MMP3 P08254 2/20 0.42
MMP9 P14780 2/20 0.42
MMP8 P22894 2/20 0.42
MMP1 P03956 1/20 0.42
CTSS P25774 1/20 0.41
EPHX2 P34913 2/20 0.41
TLR2 O60603 1/20 0.40
TLR1 Q15399 1/20 0.40
TEAD3 Q99594 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600024 0.99 L3MBTL1 (0.57) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL18282351 0.99 L3MBTL1 (0.57) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL17940942 0.99 L3MBTL1 (0.57) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL17941127 0.97 L3MBTL1 (0.59) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL17941107 0.97 L3MBTL1 (0.62) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL16346501 0.96 L3MBTL1 (0.54) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL17940957 0.96 L3MBTL1 (0.54) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL18530395 0.96 L3MBTL1 (0.54) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL26116555 0.96 L3MBTL1 (0.54) L3MBTL1PPARATDP1PPARGMMP3
SCHEMBL4140935 0.96 L3MBTL1 (0.56) L3MBTL1PPARATDP1PPARGMMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361248-A1 PROTAC COMPOUND WITH CYCLOPHILIN A DEGRADATION ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF Shenzhen Bay Laboratory (CN) 2025-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361248-A1 PROTAC COMPOUND WITH CYCLOPHILIN A DEGRADATION ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF PPIA, PPIG, PPIF L3MBTL1 4638/4885PPARA 591/4885TDP1 3463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.