SCHEMBL31735398

SCHEMBL31735398

Cc1c(Nc2ccc3c(ccn3C3CCN(S(C)(=O)=O)C3)c2)cnn(C)c1=O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 3/20 0.37
▸ BRD9 Q9H8M2 3/20 0.37
▸ WEE1 P30291 5/20 0.36
▸ BPTF Q12830 4/20 0.35
▸ KAT2B Q92831 4/20 0.34
▸ MTOR P42345 1/20 0.33
▸ PRKDC P78527 1/20 0.33
▸ BRPF1 P55201 1/20 0.33
▸ BRD7 Q9NPI1 1/20 0.33
▸ LRRK2 Q5S007 2/20 0.33
▸ ACHE P22303 1/20 0.33
▸ PTGS2 P35354 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ PDE4A P27815 1/20 0.32
▸ PDE4B Q07343 1/20 0.32
▸ PDE4C Q08493 1/20 0.32
▸ PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735476 0.86 BRD4 (0.40) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735728 0.84 BRD4 (0.39) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735682 0.84 BRD4 (0.39) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735773 0.84 BRD4 (0.39) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735652 0.82 BRD4 (0.40) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735740 0.82 TBK1 (0.38) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735692 0.82 EGFR (0.37) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735533 0.82 EGFR (0.37) BRD4BRD9WEE1BPTFKAT2B
SCHEMBL31735471 0.81 BPTF (0.40) BRD4BRD9BPTFKAT2B
SCHEMBL31735748 0.80 BPTF (0.40) BRD4BRD9BPTFKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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