SCHEMBL31735740

SCHEMBL31735740

Cc1c(Nc2ccc3c(ccn3C3CCN(C(=O)CO)C3)c2)cnn(C)c1=O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TBK1 Q9UHD2 2/20 0.38
▸ EGFR P00533 5/20 0.37
▸ CSF1R P07333 4/20 0.37
▸ WEE1 P30291 4/20 0.36
▸ MTOR P42345 4/20 0.35
▸ PIK3CA P42336 3/20 0.35
▸ BRD4 O60885 2/20 0.34
▸ BRD9 Q9H8M2 2/20 0.34
▸ BPTF Q12830 1/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ JAK1 P23458 1/20 0.33
▸ JAK3 P52333 1/20 0.33
▸ KAT2B Q92831 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735703 0.93 PKM (0.37) TBK1EGFRCSF1RWEE1MTOR
SCHEMBL31735728 0.91 BRD4 (0.39) EGFRCSF1RWEE1BRD4BRD9
SCHEMBL31735773 0.91 BRD4 (0.39) EGFRCSF1RWEE1BRD4BRD9
SCHEMBL31735682 0.91 BRD4 (0.39) EGFRCSF1RWEE1BRD4BRD9
SCHEMBL31735692 0.88 EGFR (0.37) EGFRCSF1RWEE1MTORPIK3CA
SCHEMBL31735533 0.88 EGFR (0.37) EGFRCSF1RWEE1MTORPIK3CA
SCHEMBL31735652 0.87 BRD4 (0.40) WEE1BRD4BRD9BPTFJAK2
SCHEMBL31735591 0.86 WEE1 (0.43) EGFRWEE1MTORPIK3CAJAK2
SCHEMBL31735539 0.85 BRD4 (0.39) WEE1BRD4BRD9BPTFKAT2B
SCHEMBL31735476 0.82 BRD4 (0.40) WEE1BRD4BRD9BPTFKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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