SCHEMBL31735480

SCHEMBL31735480

Cc1c(Nc2ccc3[nH]ccc3c2C)cnn(C)c1=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 2/20 0.46
▸ BRD4 O60885 4/20 0.44
▸ BRD9 Q9H8M2 4/20 0.44
▸ PRKCQ Q04759 14/20 0.41
▸ PRKCD Q05655 14/20 0.41
▸ PRKCB P05771 1/20 0.38
▸ LCK P06239 1/20 0.38
▸ LYN P07948 1/20 0.38
▸ PRKCH P24723 1/20 0.38
▸ PRKCE Q02156 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735496 0.89 BRD4 (0.42) P2RX7BRD4BRD9
SCHEMBL31735858 0.85 BRD9 (0.43) P2RX7BRD4BRD9PRKCQPRKCD
SCHEMBL31735495 0.84 BRD9 (0.44) P2RX7BRD4BRD9
SCHEMBL31735487 0.83 BRD9 (0.41) P2RX7BRD4BRD9PRKCQPRKCD
SCHEMBL31735880 0.82 BRD9 (0.41) P2RX7BRD4BRD9PRKCQPRKCD
SCHEMBL31735955 0.81 BRD9 (0.41) P2RX7BRD4BRD9
SCHEMBL31735512 0.81 BRD9 (0.41) P2RX7BRD4BRD9
SCHEMBL31735761 0.81 BRD9 (0.39) P2RX7BRD4BRD9PRKCQPRKCD
SCHEMBL31735622 0.81 BRD9 (0.43) P2RX7BRD4BRD9
SCHEMBL31735599 0.80 BRD9 (0.45) BRD4BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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