SCHEMBL31735496

SCHEMBL31735496

Cc1c(Nc2ccc3[nH]ccc3c2Cl)cnn(C)c1=O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 11/20 0.42
▸ BRD9 Q9H8M2 10/20 0.42
▸ BPTF Q12830 9/20 0.42
▸ KAT2B Q92831 8/20 0.42
▸ P2RX7 Q99572 1/20 0.38
▸ KAT2A Q92830 1/20 0.37
▸ CECR2 Q9BXF3 1/20 0.37
▸ BRD7 Q9NPI1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735480 0.89 P2RX7 (0.46) BRD4BRD9P2RX7
SCHEMBL31735487 0.85 BRD9 (0.41) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735791 0.83 BRD4 (0.41) BRD4BRD9BPTFKAT2B
SCHEMBL31735622 0.82 BRD9 (0.43) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735858 0.82 BRD9 (0.43) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735599 0.79 BRD9 (0.45) BRD4BRD9BPTFKAT2BKAT2A
SCHEMBL31735955 0.79 BRD9 (0.41) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735495 0.79 BRD9 (0.44) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735512 0.79 BRD9 (0.41) BRD4BRD9BPTFKAT2BP2RX7
SCHEMBL31735454 0.78 BRD4 (0.45) BRD4BRD9BPTFKAT2BKAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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