SCHEMBL31735482

SCHEMBL31735482

Cc1c(Nc2cc(-c3ccccc3O)cc3c2ccn3C)cnn(C)c1=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 12/20 0.45
▸ BRD4 O60885 12/20 0.45
▸ BRPF1 P55201 1/20 0.36
▸ BRD7 Q9NPI1 1/20 0.36
▸ METAP2 P50579 1/20 0.35
▸ KAT2B Q92831 5/20 0.34
▸ BPTF Q12830 2/20 0.34
▸ HSD11B1 P28845 2/20 0.34
▸ COMT P21964 1/20 0.33
▸ POLQ O75417 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735641 0.90 BRD4 (0.47) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735477 0.81 BRD4 (0.41) BRD9BRD4BRPF1BRD7METAP2
SCHEMBL31735545 0.79 BRD4 (0.43) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735491 0.77 BRD4 (0.37) BRD9BRD4
SCHEMBL31735753 0.76 BRD4 (0.48) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735409 0.73 BRD9 (0.47) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735454 0.72 BRD4 (0.45) BRD9BRD4BRD7KAT2BBPTF
SCHEMBL31735630 0.72 BRD4 (0.45) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735656 0.70 BRD9 (0.41) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735702 0.66 BRD4 (0.70) BRD9BRD4BRPF1BRD7KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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