SCHEMBL31735656

SCHEMBL31735656

Cc1c(Nc2ccc3[nH]ccc3c2-c2ccccc2O)cnn(C)c1=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 8/20 0.41
▸ BRD4 O60885 7/20 0.41
▸ PRKCQ Q04759 7/20 0.37
▸ PRKCD Q05655 7/20 0.37
▸ BPTF Q12830 2/20 0.34
▸ KAT2B Q92831 2/20 0.34
▸ BRPF1 P55201 1/20 0.34
▸ BRD7 Q9NPI1 1/20 0.34
▸ P2RX7 Q99572 1/20 0.34
▸ MAPK14 Q16539 1/20 0.33
▸ LYN P07948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735880 0.83 BRD9 (0.41) BRD9BRD4PRKCQPRKCDBPTF
SCHEMBL31735525 0.82 MAPK14 (0.41) BRD9BRD4BPTFKAT2BBRPF1
SCHEMBL31735480 0.81 P2RX7 (0.46) BRD9BRD4PRKCQPRKCDP2RX7
SCHEMBL31735761 0.80 BRD9 (0.39) BRD9BRD4PRKCQPRKCDP2RX7
SCHEMBL31735462 0.80 BRD9 (0.41) BRD9BRD4BPTFKAT2BBRPF1
SCHEMBL31735596 0.80 BRD9 (0.39) BRD9BRD4BPTFKAT2BBRPF1
SCHEMBL31735496 0.79 BRD4 (0.42) BRD9BRD4BPTFKAT2BBRD7
SCHEMBL31735858 0.75 BRD9 (0.43) BRD9BRD4PRKCQPRKCDBPTF
SCHEMBL31735494 0.73 BRD9 (0.41) BRD9BRD4BPTFKAT2BBRPF1
SCHEMBL31735487 0.73 BRD9 (0.41) BRD9BRD4PRKCQPRKCDBPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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