SCHEMBL31735409

SCHEMBL31735409

Cc1c(Nc2ccc3c(ccn3C)c2C)cnn(C)c1=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 14/20 0.47
▸ BRD4 O60885 13/20 0.47
▸ PRKCQ Q04759 2/20 0.41
▸ PRKCD Q05655 2/20 0.41
▸ BRPF1 P55201 1/20 0.39
▸ BRD7 Q9NPI1 1/20 0.39
▸ KAT2B Q92831 6/20 0.37
▸ BPTF Q12830 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735454 0.90 BRD4 (0.45) BRD9BRD4BRD7KAT2BBPTF
SCHEMBL31735630 0.90 BRD4 (0.45) BRD9BRD4PRKCQPRKCDBRPF1
SCHEMBL31735927 0.85 BRD9 (0.43) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735545 0.80 BRD4 (0.43) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735790 0.77 BRD9 (0.46) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735804 0.77 BRD4 (0.45) BRD9BRD4KAT2BBPTF
SCHEMBL31735753 0.76 BRD4 (0.48) BRD9BRD4BRPF1BRD7KAT2B
SCHEMBL31735480 0.75 P2RX7 (0.46) BRD9BRD4PRKCQPRKCD
SCHEMBL31735878 0.75 BRD4 (0.42) BRD9BRD4KAT2BBPTF
SCHEMBL31735702 0.70 BRD4 (0.70) BRD9BRD4BRPF1BRD7KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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