SCHEMBL31735581

SCHEMBL31735581

COCCn1c(C)cc2cc(N)ccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCI P41743 1/20 0.45
▸ KDM4E B2RXH2 8/20 0.43
▸ ALDH1A1 P00352 7/20 0.43
▸ GAA P10253 3/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ BRPF1 P55201 2/20 0.43
▸ CACNA1B Q00975 1/20 0.40
▸ HPGD P15428 2/20 0.38
▸ RAD52 P43351 1/20 0.38
▸ PTGER4 P35408 1/20 0.36
▸ LMNA P02545 3/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ RECQL P46063 1/20 0.36
▸ GLA P06280 1/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ MAPT P10636 2/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10753662 0.84 KDM4E (0.45) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL31735708 0.81 PRKCI (0.38) PRKCIKDM4EALDH1A1GAABRPF1
SCHEMBL30943184 0.80 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ACACNA1BHPGD
SCHEMBL28101671 0.80 PTGER4 (0.47) PRKCIKDM4EALDH1A1GAAMEN1
SCHEMBL2126643 0.80 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ACACNA1BHPGD
SCHEMBL9581422 0.79 TP53 (0.54) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2263609 0.78 HTR6 (0.49) PRKCIKDM4EALDH1A1GAAMEN1
SCHEMBL31735392 0.77 TDP1 (0.56) KDM4EALDH1A1SMN1; SMN2CACNA1BHPGD
SCHEMBL2123828 0.77 CACNA1B (0.43) PRKCIKDM4EALDH1A1GAAMEN1
SCHEMBL23045682 0.77 KDM4E (0.49) KDM4EGAAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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