SCHEMBL31735653

SCHEMBL31735653

COCCn1ccc2c(Nc3cnn(C)c(=O)c3C)c(C)ccc21

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 14/20 0.45
▸ BRD9 Q9H8M2 13/20 0.45
▸ BRPF1 P55201 1/20 0.37
▸ BRD7 Q9NPI1 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.35
▸ KAT2B Q92831 5/20 0.34
▸ GRIN2B Q13224 1/20 0.34
▸ TP53 P04637 1/20 0.32
▸ BPTF Q12830 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735746 0.90 BRD4 (0.42) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735860 0.85 BRD4 (0.44) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735819 0.82 BRD4 (0.41) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735425 0.79 BRD4 (0.41) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735688 0.79 BRD4 (0.42) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735592 0.79 BRD9 (0.42) BRD4BRD9BRPF1BRD7RXFP1
SCHEMBL31735513 0.78 BRD9 (0.42) BRD4BRD9BRPF1BRD7RXFP1
SCHEMBL31735825 0.77 BRD9 (0.40) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735517 0.77 BRD4 (0.41) BRD4BRD9BRPF1BRD7KAT2B
SCHEMBL31735396 0.77 BRD9 (0.40) BRD4BRD9BRPF1BRD7KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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