SCHEMBL31735670

SCHEMBL31735670

Cc1c(Nc2cc3ccn(CCC4CCNCC4)c3cc2Cl)cnn(C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 8/20 0.39
▸ BPTF Q12830 9/20 0.38
▸ BRD4 O60885 7/20 0.36
▸ STK4 Q13043 1/20 0.35
▸ STK3 Q13188 1/20 0.35
▸ SIK2 Q9H0K1 1/20 0.35
▸ STK26 Q9P289 1/20 0.35
▸ STK24 Q9Y6E0 1/20 0.35
▸ KAT2B Q92831 2/20 0.34
▸ NMT1 P30419 2/20 0.33
▸ BRPF1 P55201 1/20 0.33
▸ BRD7 Q9NPI1 1/20 0.33
▸ NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735743 0.86 NR3C1 (0.38) BRD9BPTFBRD4NR3C1
SCHEMBL31735427 0.85 BRD9 (0.42) BRD9BPTFBRD4KAT2BBRPF1
SCHEMBL31735869 0.83 PIK3CA (0.39) BRD4
SCHEMBL31735742 0.80 BPTF (0.52) BRD9BPTFBRD4KAT2BBRD7
SCHEMBL31735878 0.78 BRD4 (0.42) BRD9BPTFBRD4KAT2B
SCHEMBL31735640 0.76 BRD9 (0.41) BRD9BPTFBRD4KAT2BBRPF1
SCHEMBL31735634 0.72 NR3C1 (0.38) BRD9BPTFBRD4BRPF1BRD7
SCHEMBL31735748 0.69 BPTF (0.40) BRD9BPTFBRD4KAT2B
SCHEMBL31735506 0.69 BRD9 (0.41) BRD9BPTFBRD4KAT2B
SCHEMBL15604166 0.68 PRKCI (0.43) BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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