SCHEMBL31735539

SCHEMBL31735539

CC(=O)N1CC(n2ccc3cc(Nc4cnn(C)c(=O)c4C)ccc32)C1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 8/20 0.39
▸ CREBBP Q92793 2/20 0.39
▸ BPTF Q12830 9/20 0.37
▸ BRD9 Q9H8M2 5/20 0.36
▸ KAT2B Q92831 2/20 0.36
▸ PDE7A Q13946 1/20 0.34
▸ BCL6 P41182 1/20 0.33
▸ NCOR2 Q9Y618 1/20 0.33
▸ PFKFB3 Q16875 2/20 0.33
▸ WEE1 P30291 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735682 0.93 BRD4 (0.39) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735728 0.93 BRD4 (0.39) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735773 0.93 BRD4 (0.39) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735652 0.91 BRD4 (0.40) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735476 0.89 BRD4 (0.40) BRD4BPTFBRD9KAT2BWEE1
SCHEMBL31735439 0.88 P2RX3 (0.41) BPTFWEE1
SCHEMBL31735740 0.85 TBK1 (0.38) BRD4BPTFBRD9KAT2BWEE1
SCHEMBL31735692 0.85 EGFR (0.37) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735533 0.85 EGFR (0.37) BRD4CREBBPBPTFBRD9KAT2B
SCHEMBL31735471 0.84 BPTF (0.40) BRD4BPTFBRD9KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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