SCHEMBL31735771

SCHEMBL31735771

Cc1noc(C)c1-c1ccc2[nH]ccc2c1Cl

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 14/20 0.51
▸ JAK2 O60674 1/20 0.43
▸ BRD2 P25440 3/20 0.39
▸ BRD3 Q15059 2/20 0.39
▸ EZH2 Q15910 2/20 0.39
▸ CREBBP Q92793 1/20 0.38
▸ ATR Q13535 1/20 0.37
▸ MLYCD O95822 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735650 0.80 BRD4 (0.51) BRD4JAK2BRD2BRD3EZH2
SCHEMBL31735649 0.73 BRD4 (0.60) BRD4JAK2BRD2CREBBP
SCHEMBL1779422 0.70 ATR (0.53) BRD4JAK2ATR
SCHEMBL7334380 0.69 PRKAB2 (0.38) —
SCHEMBL13733723 0.68 BRD4 (0.56) BRD4BRD2BRD3CREBBP
SCHEMBL17807846 0.68 BRD4 (0.57) BRD4JAK2BRD2CREBBPATR
SCHEMBL31735610 0.68 BRD4 (1.00) BRD4JAK2BRD2BRD3CREBBP
SCHEMBL16059774 0.68 BRD4 (1.00) BRD4JAK2BRD2BRD3CREBBP
SCHEMBL12346350 0.68 AXL (0.48) BRD4BRD2CREBBPATR
SCHEMBL17467706 0.67 BRD4 (0.45) BRD4BRD2BRD3CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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