SCHEMBL31735826

SCHEMBL31735826

Cc1c(Nc2ccc3c(c2)CCNC3)cnn(C)c1=O

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 3/20 0.78
▸ BRD9 Q9H8M2 3/20 0.45
▸ BRD4 O60885 2/20 0.45
▸ BTK Q06187 4/20 0.45
▸ WEE1 P30291 6/20 0.44
▸ KAT2B Q92831 1/20 0.42
▸ AXL P30530 1/20 0.41
▸ TYRO3 Q06418 1/20 0.41
▸ MERTK Q12866 1/20 0.41
▸ DDB1 Q16531 1/20 0.41
▸ CRBN Q96SW2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26910161 0.88 BPTF (1.00) BPTFBRD9BRD4BTKKAT2B
SCHEMBL26910168 0.83 BPTF (1.00) BPTFBRD9BRD4BTKKAT2B
SCHEMBL31735865 0.75 BPTF (0.50) BPTFBRD9BRD4KAT2BDDB1
SCHEMBL10265028 0.74 BPTF (0.57) BPTFBTKWEE1DDB1CRBN
SCHEMBL13763484 0.72 BPTF (0.53) BPTFBTKWEE1
SCHEMBL26910192 0.71 BPTF (1.00) BPTFBRD9BRD4KAT2B
SCHEMBL31735413 0.71 BPTF (0.95) BPTFBRD9BRD4KAT2B
SCHEMBL2583600 0.71 BPTF (0.54) BPTFBTKWEE1
SCHEMBL31735885 0.71 BRD4 (0.44) BPTFBRD9BRD4KAT2B
SCHEMBL31735366 0.71 BRD4 (0.44) BPTFBRD9BRD4KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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