Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.54 |
| ▸ | WEE1 | P30291 | 17/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393416 | 0.80 | BPTF (0.53) | BPTFWEE1BTK | |
| SCHEMBL10265028 | 0.72 | BPTF (0.57) | BPTFWEE1BTK | |
| SCHEMBL31735826 | 0.71 | BPTF (0.78) | BPTFWEE1BTK | |
| SCHEMBL26910161 | 0.70 | BPTF (1.00) | BPTFBTK | |
| SCHEMBL13303669 | 0.70 | DHODH (0.45) | BPTF | |
| SCHEMBL8240279 | 0.69 | AURKA (0.58) | — | |
| SCHEMBL1392909 | 0.69 | BPTF (0.41) | BPTFWEE1BTK | |
| SCHEMBL13763484 | 0.68 | BPTF (0.53) | BPTFWEE1BTK | |
| SCHEMBL16847015 | 0.68 | ASIC3 (0.55) | BPTF | |
| SCHEMBL24865355 | 0.67 | PNMT (0.53) | BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566869-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | Gilead Connecticut, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140488-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT, INC. (US) | 2011-11-10 | — | — | WO | disclosed |