SCHEMBL31735865

SCHEMBL31735865

Cc1c(Nc2ccc3c(c2)C(=O)N(C)C3)cnn(C)c1=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 11/20 0.50
▸ BRD4 O60885 9/20 0.47
▸ BRD9 Q9H8M2 9/20 0.47
▸ KAT2B Q92831 4/20 0.44
▸ DDB1 Q16531 1/20 0.43
▸ CRBN Q96SW2 1/20 0.43
▸ MKNK1 Q9BUB5 1/20 0.40
▸ BRD7 Q9NPI1 2/20 0.39
▸ BRPF1 P55201 1/20 0.39
▸ APP P05067 1/20 0.38
▸ KAT2A Q92830 1/20 0.38
▸ CECR2 Q9BXF3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735826 0.75 BPTF (0.78) BPTFBRD4BRD9KAT2BDDB1
SCHEMBL31735702 0.73 BRD4 (0.70) BPTFBRD4BRD9KAT2BBRD7
SCHEMBL14566645 0.72 DDB1 (0.54) DDB1CRBNMKNK1APP
SCHEMBL31735804 0.72 BRD4 (0.45) BPTFBRD4BRD9KAT2B
SCHEMBL31735852 0.72 RAB9A (0.48) BPTFBRD4BRD9KAT2B
SCHEMBL31735890 0.72 BRD4 (0.45) BPTFBRD4BRD9KAT2BBRD7
SCHEMBL31735514 0.71 BRD4 (0.44) BPTFBRD4BRD9KAT2B
SCHEMBL31735933 0.71 BRD4 (0.44) BPTFBRD4BRD9KAT2BBRD7
SCHEMBL31735744 0.71 BRD4 (0.44) BPTFBRD4BRD9KAT2BBRD7
SCHEMBL31735366 0.71 BRD4 (0.44) BPTFBRD4BRD9KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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