SCHEMBL31735846

SCHEMBL31735846

COCCn1ccc2cc(Nc3c(C)nn(C)c(=O)c3C)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 2/20 0.40
▸ EGFR P00533 5/20 0.37
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ HDAC6 Q9UBN7 1/20 0.36
▸ NCOR2 Q9Y618 1/20 0.36
▸ USP2 O75604 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CLK4 Q9HAZ1 1/20 0.36
▸ P2RX3 P56373 3/20 0.35
▸ HTR6 P50406 1/20 0.35
▸ MTNR1A P48039 1/20 0.34
▸ MTNR1B P49286 1/20 0.34
▸ ERBB2 P04626 1/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.34
▸ NTSR1 P30989 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735425 0.82 BRD4 (0.41) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735768 0.82 GLO1 (0.40) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735661 0.80 GLO1 (0.40) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735659 0.78 GLO1 (0.44) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735683 0.78 BRAF (0.38) CLK4RXFP1
SCHEMBL31735643 0.76 GLO1 (0.44) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735377 0.75 GLO1 (0.47) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735793 0.75 BPTF (0.51) —
SCHEMBL31735612 0.75 BPTF (0.49) GLO1EGFRHDAC3HDAC1HDAC2
SCHEMBL31735820 0.75 GLO1 (0.42) GLO1EGFRHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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