SCHEMBL31735377

SCHEMBL31735377

COCCn1ccc2cc(Nc3ccn(C)c(=O)c3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 2/20 0.47
▸ MTNR1A P48039 2/20 0.40
▸ MTNR1B P49286 2/20 0.40
▸ HDAC3 O15379 1/20 0.39
▸ HDAC1 Q13547 1/20 0.39
▸ HDAC2 Q92769 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ NCOR2 Q9Y618 1/20 0.39
▸ PSMB5 P28074 1/20 0.39
▸ EGFR P00533 2/20 0.38
▸ HTR6 P50406 4/20 0.38
▸ CNR2 P34972 1/20 0.36
▸ P2RX3 P56373 1/20 0.36
▸ MAOA P21397 1/20 0.36
▸ MAOB P27338 1/20 0.36
▸ ALOX5 P09917 1/20 0.36
▸ EPHX2 P34913 1/20 0.36
▸ NOTUM Q6P988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735643 0.84 GLO1 (0.44) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735820 0.82 GLO1 (0.42) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735420 0.81 GLO1 (0.41) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735938 0.80 MEN1 (0.47) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735659 0.79 GLO1 (0.44) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL13537466 0.78 GLO1 (0.47) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL28983113 0.77 GLO1 (0.45) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735846 0.75 GLO1 (0.40) GLO1MTNR1AMTNR1BHDAC3HDAC1
SCHEMBL31735425 0.74 BRD4 (0.41) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735768 0.74 GLO1 (0.40) GLO1MTNR1AMTNR1BHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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