SCHEMBL31736534

SCHEMBL31736534

CC(C)(C)OC(=O)N1CCC(O)(c2ccc3c(c2F)CN(C2CCC(=O)NC2=O)C3=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 15/20 0.46
▸ IKZF2 Q9UKS7 4/20 0.46
▸ IKZF1 Q13422 4/20 0.45
▸ CSNK1A1 P48729 1/20 0.44
▸ DDB1 Q16531 8/20 0.44
▸ IKZF3 Q9UKT9 4/20 0.43
▸ BRD4 O60885 1/20 0.43
▸ TNF P01375 1/20 0.43
▸ IL1B P01584 1/20 0.43
▸ MAP1LC3B Q9GZQ8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19585563 0.88 CRBN (0.55) CRBNIKZF1CSNK1A1DDB1IKZF3
SCHEMBL20231931 0.85 CRBN (0.51) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL29927258 0.85 CRBN (0.51) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL22345825 0.85 IKZF2 (0.61) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL31025903 0.85 IKZF2 (0.61) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL30047364 0.84 CRBN (0.49) CRBNIKZF1DDB1IKZF3TNF
SCHEMBL27157350 0.84 CRBN (0.49) CRBNIKZF1DDB1IKZF3TNF
SCHEMBL31736558 0.83 CRBN (0.48) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL24718690 0.83 CRBN (0.42) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL31023219 0.83 CRBN (0.42) CRBNIKZF2IKZF1CSNK1A1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 — — WO disclosed
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