SCHEMBL31736558

SCHEMBL31736558

CC(C)(C)OC(=O)N1CCC(O)(c2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3)CC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.48
▸ DDB1 Q16531 3/20 0.45
▸ IKZF2 Q9UKS7 2/20 0.44
▸ IKZF1 Q13422 1/20 0.44
▸ CSNK1A1 P48729 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31072968 0.86 CRBN (0.54) CRBNDDB1
SCHEMBL20231914 0.85 CRBN (0.53) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL29546738 0.85 CRBN (0.53) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL23306591 0.85 CRBN (0.54) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL22345848 0.85 IKZF2 (0.59) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL29712444 0.85 CRBN (0.54) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL31073369 0.83 CRBN (0.46) CRBNDDB1IKZF2CSNK1A1
SCHEMBL31736534 0.83 CRBN (0.46) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL30984801 0.83 CRBN (0.47) CRBNDDB1IKZF2IKZF1CSNK1A1
SCHEMBL30591574 0.82 CRBN (0.46) CRBNDDB1IKZF2CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 — — WO disclosed
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