Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.51 |
| ▸ | GRM5 | P41594 | 11/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167704 | 0.88 | GRM1 (0.53) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL15756310 | 0.88 | GRM1 (0.55) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL12740696 | 0.86 | GRM1 (0.54) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL15756312 | 0.85 | GRM1 (0.59) | GRM1GRM5PDK4PDE10ACYP11B2 | |
| SCHEMBL18009522 | 0.85 | GRM1 (0.53) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL29138576 | 0.85 | GRM1 (0.53) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL64701 | 0.85 | GRM1 (0.55) | GRM1GRM5TNK2PDK4CYP11B2 | |
| SCHEMBL15001430 | 0.84 | GRM1 (0.52) | GRM1GRM5PDK4CYP11B2NAMPT | |
| SCHEMBL30493352 | 0.84 | GPR119 (0.49) | GRM1GRM5TNK2PDK4CDK7 | |
| SCHEMBL7470566 | 0.84 | GRM5 (0.60) | GRM1GRM5TNK2PDK4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245178-A1 | PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | INNOVO THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |