Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL2689215 | 0.88 | LMNA (0.75) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL28014619 | 0.88 | LMNA (0.75) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL28154998 | 0.88 | LMNA (0.82) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL281913 | 0.86 | LMNA (0.78) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL11083521 | 0.86 | LMNA (0.86) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL1275427 | 0.86 | LMNA (0.86) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL28177337 | 0.85 | LMNA (0.69) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL5968800 | 0.84 | LMNA (0.62) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL8876737 | 0.83 | LMNA (0.90) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL6056301 | 0.83 | LMNA (0.90) | LMNAMAPK1HPGDCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025244936-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |