Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL28014619 | 0.92 | LMNA (0.75) | LMNAMAPK1NAAAHPGDCES2 | |
| Mandelic Acid SCHEMBL1672106 | 0.90 | LMNA (0.78) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL8744861 | 0.90 | LMNA (0.78) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL28168048 | 0.90 | LMNA (0.60) | LMNAMAPK1NAAAHPGDHRH1 | |
| Mandelic Acid SCHEMBL28154998 | 0.88 | LMNA (0.82) | LMNAMAPK1NAAAHPGDCES2 | |
| Mandelic Acid SCHEMBL9393798 | 0.86 | LMNA (0.72) | LMNAMAPK1NAAAHPGDCES2 | |
| Mandelic Acid SCHEMBL1832889 | 0.86 | LMNA (0.72) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL281913 | 0.86 | LMNA (0.78) | LMNAMAPK1NAAAHPGDCES2 | |
| Mandelic Acid SCHEMBL1275427 | 0.86 | LMNA (0.86) | LMNAMAPK1HPGDCES2CES1 | |
| Mandelic Acid SCHEMBL31737068 | 0.85 | LMNA (0.69) | LMNAMAPK1NAAAHPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107200745-A | Deuterated ticagrelor derivative, preparation method and its application in anticoagulant is prepared | 浙江永宁药业股份有限公司 | 2017-09-26 | — | — | CN | claimed |
| CN-107200745-A | Deuterated ticagrelor derivative, preparation method and its application in anticoagulant is prepared | 浙江永宁药业股份有限公司 | 2017-09-26 | — | — | CN | disclosed |