Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737848 | 0.80 | MAPT (0.48) | MAPTPKMPOLBALDH1A1 | |
| SCHEMBL31737070 | 0.80 | POLB (0.53) | MAPTPKMPOLBTHRBTP53 | |
| SCHEMBL30832833 | 0.79 | PKM (0.63) | MAPTL3MBTL1PKMPOLBMAPK1 | |
| SCHEMBL20772927 | 0.79 | PKM (0.63) | MAPTL3MBTL1PKMPOLBMAPK1 | |
| SCHEMBL7164868 | 0.78 | MAPT (0.84) | MAPTL3MBTL1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7170786 | 0.77 | MAPT (0.68) | MAPTL3MBTL1MAPK1SMN1; SMN2SIRT6 | |
| SCHEMBL10360050 | 0.74 | MAPT (0.73) | MAPTL3MBTL1POLBMAPK1ALDH1A1 | |
| SCHEMBL10353546 | 0.74 | MAPT (0.72) | MAPTL3MBTL1MAPK1GAASMN1; SMN2 | |
| SCHEMBL13941340 | 0.74 | MAPT (0.59) | MAPTL3MBTL1POLBMAPK1SIRT6 | |
| SCHEMBL102602 | 0.74 | MAPT (0.77) | MAPTL3MBTL1MAPK1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |