Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737135 | 0.80 | KDM4E (0.53) | POLBTHRBTP53MAPTGAA | |
| SCHEMBL31737098 | 0.80 | MAPT (0.55) | POLBTHRBTP53MAPTGAA | |
| SCHEMBL31737545 | 0.78 | POLB (0.48) | POLBTHRBTP53MAPTGAA | |
| SCHEMBL30832795 | 0.76 | TRIM24 (0.51) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL20772684 | 0.76 | TRIM24 (0.51) | TP53MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7164883 | 0.74 | BACE1 (0.56) | POLBTHRBMAPTGAAALDH1A1 | |
| SCHEMBL10208756 | 0.73 | POLB (0.60) | POLBTHRBTP53GAASMN1; SMN2 | |
| SCHEMBL7169755 | 0.72 | BACE1 (0.51) | MAPTGAAALDH1A1HDAC1 | |
| SCHEMBL32685198 | 0.71 | POLB (0.55) | POLBTHRBTP53MAPTGAA | |
| SCHEMBL13156353 | 0.71 | POLB (0.53) | POLBTHRBTP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |