Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737545 | 0.89 | POLB (0.48) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL31737070 | 0.80 | POLB (0.53) | ALDH1A1GAAMAPTTHRBSMN1; SMN2 | |
| SCHEMBL30535169 | 0.76 | GAA (0.65) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL7993941 | 0.76 | GAA (0.65) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL1422842 | 0.75 | SMN1; SMN2 (0.71) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL21290296 | 0.72 | GAA (0.43) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL31737848 | 0.72 | MAPT (0.48) | ALDH1A1MAPTPTGER4RAB9APOLB | |
| SCHEMBL32685198 | 0.72 | POLB (0.55) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL1731245 | 0.71 | GAA (1.00) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL2687869 | 0.69 | GAA (0.77) | KDM4EALDH1A1GAAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |