Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737135 | 0.89 | KDM4E (0.53) | POLBKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL31737848 | 0.83 | MAPT (0.48) | POLBALDH1A1MAPTRAB9APTGER4 | |
| SCHEMBL31737070 | 0.78 | POLB (0.53) | POLBGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4539438 | 0.78 | ALDH1A1 (0.52) | POLBKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL7539164 | 0.78 | SMN1; SMN2 (0.65) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL14977866 | 0.77 | GAA (0.54) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL4538645 | 0.77 | MAPT (0.54) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL12004538 | 0.77 | GAA (0.54) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL15687652 | 0.77 | CA1 (0.61) | KDM4EHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL8037982 | 0.74 | KDM4E (0.54) | KDM4EHSD17B10GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |