Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | BCL6 | P41182 | 1/20 | 0.51 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034789 | 0.89 | ALDH1A1 (0.63) | MAPTPKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL8611245 | 0.85 | MAPT (0.59) | MAPTPKMLMNASMN1; SMN2ALPG | |
| SCHEMBL10996617 | 0.84 | TDP1 (0.59) | MAPTPKMLMNASMN1; SMN2ALPG | |
| SCHEMBL1520169 | 0.84 | MAPT (0.64) | MAPTPKMLMNASMN1; SMN2ALPG | |
| SCHEMBL30697331 | 0.83 | KAT2B (0.63) | MAPTALDH1A1HPGDBCL6BCOR | |
| SCHEMBL29126150 | 0.83 | KAT2B (0.63) | MAPTALDH1A1HPGDBCL6BCOR | |
| SCHEMBL9036234 | 0.82 | BCL6 (0.58) | MAPTLMNATDP1ALDH1A1HPGD | |
| SCHEMBL5026709 | 0.79 | KAT2B (0.60) | MAPTLMNASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL11793898 | 0.79 | TDP1 (0.66) | MAPTTDP1ALDH1A1HPGDKDM4E | |
| SCHEMBL6376371 | 0.78 | POLB (0.63) | MAPTPKMLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025244936-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |