Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482776 | 0.88 | ALDH1A1 (0.60) | MAPTPKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31737331 | 0.85 | MAPT (0.60) | MAPTPKMALDH1A1KDM4ELMNA | |
| SCHEMBL9368499 | 0.83 | NPSR1 (0.56) | MAPTPKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL26841476 | 0.81 | LMNA (0.61) | MAPTPKMALDH1A1KDM4ELMNA | |
| SCHEMBL6376377 | 0.81 | POLB (0.63) | MAPTPKMALDH1A1KDM4ELMNA | |
| SCHEMBL6376371 | 0.81 | POLB (0.63) | MAPTPKMALDH1A1KDM4ELMNA | |
| SCHEMBL1520169 | 0.80 | MAPT (0.64) | MAPTPKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2016758 | 0.80 | MAPT (0.63) | MAPTPKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL26125825 | 0.80 | ALDH1A1 (0.56) | MAPTPKMALDH1A1KDM4ELMNA | |
| SCHEMBL4305240 | 0.78 | SMN1; SMN2 (0.58) | MAPTALDH1A1LMNAMAPK1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |