SCHEMBL31737569

SCHEMBL31737569

CN1CC2CN(c3ncc4c(=O)c(C(=O)O)c5sc6ccccc6n5c4n3)CC2C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 2/20 0.34
KDM4E B2RXH2 4/20 0.34
CASP1 P29466 3/20 0.34
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 3/20 0.33
HPGD P15428 2/20 0.33
ACHE P22303 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 3/20 0.33
USP2 O75604 2/20 0.33
CYP1A2 P05177 2/20 0.33
CASP7 P55210 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31737273 1.00 RBP4 (0.34) RBP4KDM4ECASP1LMNAL3MBTL1
SCHEMBL31737861 0.92 CAMK2D (0.35) KDM4ECASP1LMNAL3MBTL1HSD17B10
SCHEMBL31737581 0.91 HCRTR2 (0.40) HCRTR2HCRTR1
SCHEMBL31737869 0.91 KDM4E (0.33) KDM4ECASP1L3MBTL1ACHEMAPK1
SCHEMBL31648858 0.91 PTPN11 (0.35) RBP4KDM4ECASP1LMNAL3MBTL1
SCHEMBL31649249 0.89 MAPT (0.35) KDM4ELMNAHSD17B10HPGDACHE
SCHEMBL31737401 0.88 KDM4E (0.37) KDM4EALDH1A1HCRTR2HCRTR1
SCHEMBL31649259 0.88 MAPK1 (0.33) CASP1LMNAMAPK1
SCHEMBL31629625 0.88 CYP1A2 (0.35) KDM4ECASP1LMNAL3MBTL1HSD17B10
SCHEMBL31737844 0.87 PDE4A (0.33) KDM4EL3MBTL1MAPK1CYP1A2HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242908-A2 NOVEL COMPOUNDS GENOME THERAPEUTICS LTD (GB) 2025-11-27 WO disclosed