SCHEMBL31738151

SCHEMBL31738151

Cc1ncnc(N2CCN(Cc3nc4ccc(C(C)(C)O)cc4o3)CC2)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
LMNA P02545 2/20 0.41
SOS1 Q07889 1/20 0.39
CACNA1G O43497 2/20 0.37
KCNH2 Q12809 2/20 0.37
PIK3CA P42336 2/20 0.36
MTOR P42345 2/20 0.36
RPS6KB1 P23443 1/20 0.34
MAPK1 P28482 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30040088 0.89 RPS6KB1 (0.44) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL23932507 0.89 RPS6KB1 (0.44) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL31737700 0.86 TP53 (0.44) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL25510924 0.86 LMNA (0.55) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL31737718 0.84 LMNA (0.44) TP53LMNASOS1PIK3CAMTOR
SCHEMBL23932567 0.84 HTT (0.47) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL23932566 0.84 SOS1 (0.57) TP53LMNASOS1RPS6KB1HTT
SCHEMBL30297611 0.84 SOS1 (0.57) TP53LMNASOS1RPS6KB1HTT
SCHEMBL23932521 0.84 HTT (0.47) TP53LMNASOS1CACNA1GKCNH2
SCHEMBL30041055 0.84 HTT (0.47) TP53LMNASOS1CACNA1GKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245046-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2025-11-27 WO disclosed