SCHEMBL31738422

SCHEMBL31738422

O=C1NC(=O)[C@@H](c2ccccc2)N1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.66
MAPT P10636 5/20 0.54
ALDH1A1 P00352 4/20 0.54
USP2 O75604 1/20 0.54
MAPK10 P53779 1/20 0.54
LMNA P02545 3/20 0.50
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
ADORA3 P0DMS8 1/20 0.46
HSD17B10 Q99714 2/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
GAA P10253 2/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395878 1.00 TDP1 (0.66) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL19955179 1.00 TDP1 (0.66) TDP1MAPTALDH1A1USP2MAPK10
Nitrous Acid SCHEMBL7062049 0.91 TDP1 (0.56) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL13527924 0.89 TDP1 (0.80) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1624200 0.88 TDP1 (0.62) TDP1MAPTALDH1A1USP2MAPK10
Hydantoin SCHEMBL8764797 0.86 TDP1 (0.51) TDP1MAPTALDH1A1USP2MAPK10
Methane SCHEMBL11336749 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1895535 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1894049 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL15669931 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121022808-A Mutant of D-hydantoin enzyme and application thereof 浙江云涛生物技术股份有限公司 2025-11-28 CN disclosed