Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395878 | 0.86 | TDP1 (0.66) | TDP1MAPTALDH1A1USP2MAPK10 | |
| SCHEMBL31738422 | 0.86 | TDP1 (0.66) | TDP1MAPTALDH1A1USP2MAPK10 | |
| SCHEMBL19955179 | 0.86 | TDP1 (0.66) | TDP1MAPTALDH1A1USP2MAPK10 | |
| SCHEMBL27560838 | 0.84 | TDP1 (0.63) | TDP1MAPTALDH1A1USP2MAPK10 | |
| Nitrous Acid SCHEMBL7062049 | 0.78 | TDP1 (0.56) | TDP1MAPTALDH1A1USP2MAPK10 | |
| SCHEMBL13527924 | 0.76 | TDP1 (0.80) | TDP1MAPTALDH1A1USP2MAPK10 | |
| Hydantoin SCHEMBL27574136 | 0.76 | CRBN (0.46) | TDP1MAPTALDH1A1DDB1CRBN | |
| SCHEMBL1624200 | 0.76 | TDP1 (0.62) | TDP1MAPTALDH1A1USP2MAPK10 | |
| SCHEMBL4477872 | 0.75 | DDB1 (0.46) | MAPTALDH1A1USP2MAPK10DDB1 | |
| SCHEMBL28359790 | 0.75 | DDB1 (0.46) | MAPTALDH1A1USP2MAPK10DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677585-B1 | Process for the production of D-alpha-amino acids | ENIRICERCHE SPA (IT) | 1997-07-23 | — | — | EP | claimed |