SCHEMBL395878

SCHEMBL395878

O=C1NC(=O)C(c2ccccc2)N1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.66
MAPT P10636 5/20 0.54
ALDH1A1 P00352 4/20 0.54
USP2 O75604 1/20 0.54
MAPK10 P53779 1/20 0.54
LMNA P02545 3/20 0.50
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
ADORA3 P0DMS8 1/20 0.46
HSD17B10 Q99714 2/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
GAA P10253 2/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31738422 1.00 TDP1 (0.66) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL19955179 1.00 TDP1 (0.66) TDP1MAPTALDH1A1USP2MAPK10
Nitrous Acid SCHEMBL7062049 0.91 TDP1 (0.56) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL13527924 0.89 TDP1 (0.80) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1624200 0.88 TDP1 (0.62) TDP1MAPTALDH1A1USP2MAPK10
Hydantoin SCHEMBL8764797 0.86 TDP1 (0.51) TDP1MAPTALDH1A1USP2MAPK10
Methane SCHEMBL11336749 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1895535 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL1894049 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10
SCHEMBL15669931 0.81 MAPT (0.48) TDP1MAPTALDH1A1USP2MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955391-A Substituted N- (2-oxo ethyl) benzamide derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-11-15 CN claimed
CN-118904163-A Preparation method and device for preparing phenylglycine by using pipelining continuous flow 海连化工科技(绍兴)有限公司 2024-11-08 CN claimed
CN-118667895-A Improved production process of p-hydroxyphenylglycine by enzyme method 联邦制药(内蒙古)有限公司 2024-09-20 CN claimed
CN-117816204-A Floating catalyst and application thereof in synthesizing p-hydroxy-phenylhydantoin 天津市职业大学 2024-04-05 CN claimed
CN-220664953-U Mother liquor recycling system for phenylhydantoin production 内蒙古天宇达生物科技有限公司 2024-03-26 CN claimed
CN-116686826-A Air slow-release sterilization gel and preparation method thereof 河北鑫淘沅医药科技有限公司 2023-09-05 CN claimed
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN claimed
CN-111847446-B Aza-hybridized mesoporous carbon and preparation method thereof 天津市职业大学 2023-05-26 CN claimed
CN-116063818-A Epoxy resin composition, preparation method and application thereof, LED display screen, packaging method of LED display screen and electronic product 深圳市洲明科技股份有限公司 2023-05-05 CN claimed
CN-110330460-B Preparation method of p-hydroxy-phenyl-hydantoin 中国科学技术大学 2023-02-21 CN claimed
EP-0093465-A2 Preparation of 6-alpha-bromo- and/or 6,6-dibromo-penicillanic acid 1,1-dioxides GIST-BROCADES N.V. (NL) 1983-11-09 EP claimed
US-4312948-A AGROBACTERIUM CULTURE SNAMPROGETTI S.P.A. (IT) 1982-01-26 US claimed
US-4304782-A ANNATO, PAPRIKA, CARROT OIL, YELLOW VEGETABLE OIL REGION WALLONNE (BE) 1981-12-08 US claimed
US-4248967-A BY HYDROLYSIS AND RESOLUTION SNAMPROGETTI S.P.A. (IT) 1981-02-03 US claimed
US-4230562-A USING SOYBEAN LECITHIN AND OXAMIDE AS NUTRIENTS FOR MICROORGANISMS FOR BIODEGRADATION SNAMPROGETTI S.P.A. (IT) 1980-10-28 US claimed
EP-0015038-A1 Pharmaceutical composition containing a diphenylhydantoin derivative, derivatives used and their preparation REGION WALLONNE représentée par le Ministre des Technologies nouvelles de la region wallonne (BE) 1980-09-03 EP claimed
US-4211840-A USING ENZYME SPECIFIC FOR D-ISOMER OF 5-SUBSTITUTED HYDANTOIN AJINOMOTO COMPANY, INCORPORATED (JP) 1980-07-08 US claimed
US-4111749-A HYDROLYSIS, ENZYMATIC COMPLEX OF MICROORGANISMS DERIVED FROM PSEUDOMONAS SNAMPROGETTI, S.P.A. (IT) 1978-09-05 US claimed
US-4094741-A CULTURES, ASYMMETRIC HYDROLYSIS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1978-06-13 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed