SCHEMBL31738532

SCHEMBL31738532

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NTSR1 P30989 20/20 0.76
NTSR2 O95665 18/20 0.76
SORT1 Q99523 16/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421598 0.96 NTSR1 (0.72) NTSR1NTSR2SORT1
SCHEMBL1421605 0.96 NTSR1 (0.72) NTSR1NTSR2SORT1
SCHEMBL1421525 0.96 NTSR1 (0.72) NTSR1NTSR2SORT1
SCHEMBL1421513 0.96 NTSR1 (0.72) NTSR1NTSR2SORT1
SCHEMBL1421888 0.95 OPRD1 (0.69) NTSR1NTSR2SORT1
SCHEMBL1421906 0.95 OPRD1 (0.69) NTSR1NTSR2SORT1
SCHEMBL1421938 0.95 OPRD1 (0.69) NTSR1NTSR2SORT1
SCHEMBL1421931 0.95 OPRD1 (0.69) NTSR1NTSR2SORT1
SCHEMBL30864885 0.95 NTSR1 (0.78) NTSR1NTSR2SORT1
SCHEMBL30775521 0.94 NTSR1 (0.68) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12485191-B2 Radiopharmaceuticals and methods of use thereof BOARD OF REGENTS OF THE UNIVERISTY OF NEBRASKA (US) 2025-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485191-B2 Radiopharmaceuticals and methods of use thereof FOLH1, SSTR4, SLC18A2 NTSR1 139/4885NTSR2 77/4885SORT1 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.