Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705145 | 0.84 | PTK2 (0.63) | HPGDJAK3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25719397 | 0.84 | PTK2 (0.63) | HPGDJAK3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2797263 | 0.84 | HTR2C (0.55) | HTTKDM4ECYP1A2 | |
| SCHEMBL19827176 | 0.79 | HTR3E (0.57) | HPGDHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30821993 | 0.76 | PTK2 (0.71) | HPGDJAK3HTTLMNAALDH1A1 | |
| SCHEMBL6569122 | 0.76 | PTK2 (0.71) | HPGDJAK3HTTLMNAALDH1A1 | |
| SCHEMBL31452305 | 0.75 | PIK3CA (0.47) | HPGDHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30821962 | 0.75 | CYP1A2 (0.47) | HPGDJAK3HTTLMNAALDH1A1 | |
| SCHEMBL20589624 | 0.74 | PIK3CD (0.45) | HPGDLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29880381 | 0.74 | KIT (0.55) | JAK3HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368623-A1 | PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES | GENETIC INTELLIGENCE INC (US) | 2025-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368623-A1 | PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES | MYC, MYCBP, MKI67 | HPGD 718/4885JAK3 1764/4885HTT 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.