Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859827 | 1.00 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31741194 | 0.87 | MMP1 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL30860045 | 0.87 | MMP1 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31740434 | 0.84 | DPP4 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28721432 | 0.83 | NR1H2 (0.41) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28722417 | 0.83 | NR1H2 (0.41) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28721431 | 0.83 | NR1H2 (0.41) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12524859 | 0.81 | NR1H2 (0.46) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28719822 | 0.81 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL17079757 | 0.81 | ALDH1A1 (0.43) | NR1H2MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368625-A1 | PIPERAZINES | Grünenthal GmbH (DE) | 2025-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368625-A1 | PIPERAZINES | SSTR4, SSTR5, SSTR2 | NR1H2 478/4885MAPT 3682/4885MEN1 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.