Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 1.00 |
| ▸ | HRAS | P01112 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NRAS | P01111 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613609 | 1.00 | KRAS (1.00) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL31741902 | 1.00 | KRAS (1.00) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL17486851 | 0.81 | HRAS (0.69) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL14712382 | 0.79 | NPSR1 (0.67) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL17486850 | 0.75 | HRAS (0.60) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL23843621 | 0.73 | HRAS (0.58) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL14132207 | 0.73 | F2 (0.58) | KRASHRASNPSR1F2 | |
| SCHEMBL3897403 | 0.72 | HRAS (0.57) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL16056766 | 0.72 | HRAS (0.56) | KRASHRASMEN1HTTKMT2A | |
| SCHEMBL411104 | 0.72 | ALDH1A1 (0.79) | KRASHRASMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4659812-A1 | DETECTION METHODS AND COMBINATION THERAPIES OF CELLS WITH EXTRACELLULAR RAS EXPRESSION | Bumm, Thomas (DE) | 2025-12-10 | — | — | EP | disclosed |