Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061675 | 0.93 | REV1 (0.61) | REV1ABCB1CA2CA9KMT2A | |
| SCHEMBL3041835 | 0.84 | KDM4E (0.53) | REV1TMEM97ABCB1CA2CA9 | |
| SCHEMBL3049199 | 0.84 | REV1 (0.53) | REV1TMEM97SIGMAR1ABCB1CA2 | |
| SCHEMBL3048961 | 0.83 | ABCB1 (0.69) | REV1ABCB1CA2CA9KMT2A | |
| SCHEMBL3059191 | 0.83 | KDM4E (0.54) | REV1ABCB1CA2CA9KMT2A | |
| SCHEMBL3042196 | 0.83 | DHCR7 (0.58) | REV1TMEM97SIGMAR1ABCB1CA2 | |
| SCHEMBL3060196 | 0.83 | KDM4E (0.54) | REV1ABCB1CA2CA9KMT2A | |
| SCHEMBL3174390 | 0.83 | CA2 (0.63) | REV1TMEM97SIGMAR1ABCB1CA2 | |
| SCHEMBL3062059 | 0.83 | PDE4B (0.61) | REV1ABCB1CA2CA9KMT2A | |
| SCHEMBL3054744 | 0.82 | KMT2A (0.57) | REV1ABCB1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | REV1 1520/4885TMEM97 3497/4885SIGMAR1 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.