⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052360 | 1.00 | — | — | |
| SCHEMBL18937672 | 0.75 | SLC5A1 (0.30) | — | |
| SCHEMBL18937670 | 0.75 | SLC5A1 (0.30) | — | |
| SCHEMBL9385852 | 0.73 | IDUA (0.38) | — | |
| SCHEMBL14502569 | 0.70 | SLC5A1 (0.33) | — | |
| SCHEMBL16750227 | 0.70 | SLC5A1 (0.33) | — | |
| SCHEMBL14502570 | 0.70 | SLC5A1 (0.33) | — | |
| SCHEMBL14532806 | 0.70 | SLC5A1 (0.33) | — | |
| SCHEMBL3712330 | 0.68 | PYGB (0.47) | — | |
| SCHEMBL7052003 | 0.68 | PYGB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328243-A1 | Stilbenoid Derivatives And Their Uses | ARKANSAS STATE UNIVERSITY | 2015-11-19 | — | — | US | claimed |
| US-9095598-B2 | Stilbenoid derivatives and their uses | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-08-04 | — | — | US | claimed |
| US-9044491-B2 | Method for improving blood flow using stilbenoid derivatives | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-06-02 | — | — | US | claimed |
| US-8592458-B2 | Alpha7 nicotinic receptor selective ligands | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-11-26 | — | — | US | claimed |
| US-20120165281-A1 | STILBENOID DERIVATIVES AND THEIR USES | Arkansas State University - Jonesboro (US) | 2012-06-28 | — | — | US | claimed |
| US-20120165280-A1 | METHOD FOR IMPROVING BLOOD FLOW USING STILBENOID DERIVATIVES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-06-28 | — | — | US | claimed |
| US-20150328243-A1 | Stilbenoid Derivatives And Their Uses | ARKANSAS STATE UNIVERSITY | 2015-11-19 | — | — | US | disclosed |
| US-9095598-B2 | Stilbenoid derivatives and their uses | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-08-04 | — | — | US | disclosed |
| US-9044491-B2 | Method for improving blood flow using stilbenoid derivatives | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-06-02 | — | — | US | disclosed |
| US-8592458-B2 | Alpha7 nicotinic receptor selective ligands | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-8551963-B2 | Imidazolothiazole compounds and methods of use thereof | AMBIT BIOSCIENCES CORPORATION (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120165281-A1 | STILBENOID DERIVATIVES AND THEIR USES | Arkansas State University - Jonesboro (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120165280-A1 | METHOD FOR IMPROVING BLOOD FLOW USING STILBENOID DERIVATIVES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120070410-A1 | IMIDAZOLOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION | 2012-03-22 | — | — | US | disclosed |
| US-8093269-B2 | Alpha 7 nicotinic receptor selective ligands | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2358725-A1 | Imidazolothiazole compounds as modulators of protein kinase | Ambit Biosciences Corporation (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010054058-A1 | IMIDAZOLOTHIAZOLE COMPOUNDS AS MODULATORS OF PROTEIN KINASE | AMBIT BIOSCIENCE CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
| US-20090215705-A1 | Alpha 7 Nicotinic Receptor Selective Ligands | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| EP-1891036-A1 | ALPHA 7 NICOTINIC RECEPTOR SELECTIVE LIGANDS | University of Florida Research Foundation, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133303-A1 | ALPHA 7 NICOTINIC RECEPTOR SELECTIVE LIGANDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | WO | disclosed |