SCHEMBL7052003

SCHEMBL7052003

[O][C@]1(O)O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.47
PYGL P06737 3/20 0.47
PYGM P11217 2/20 0.47
LMNA P02545 1/20 0.41
GBA1 P04062 1/20 0.41
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3712328 1.00 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712330 1.00 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL27619105 0.93 PYGB (0.41) PYGBPYGLPYGMLMNAGBA1
SCHEMBL7742729 0.78 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL9708959 0.78 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL2353972 0.78 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL11913232 0.78 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712334 0.77 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1
SCHEMBL18927294 0.77 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3481602 0.77 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0898557-B9 WATER SOLUBLE TRI-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS HAVING INCREASED STORAGE STABILITY, SYNTHETIC PROCESSES AND INTERMEDIATES LUMIGEN INC (US) 2003-10-08 EP claimed
EP-0898557-B1 WATER SOLUBLE TRI-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS HAVING INCREASED STORAGE STABILITY, SYNTHETIC PROCESSES AND INTERMEDIATES LUMIGEN INC (US) 2003-04-23 EP claimed
EP-0757052-B1 Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions GOVERNORS OF WAYNE STATE BOARD (US) 2003-02-19 EP claimed
EP-0794987-B1 CHEMILUMINESCENT DIALKYL-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS, METHODS OF SYNTHESIS AND USE LUMIGEN INC (US) 2002-09-25 EP claimed
EP-0757248-B1 Improved capsule chemistry analytical methods employing dioxetane chemiluminescence GOVERNORS BOARD OF (US) 2001-05-23 EP claimed