Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385321 | 0.81 | GFER (0.71) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL118764 | 0.81 | GFER (0.71) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL203617 | 0.80 | GFER (1.00) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL1715319 | 0.80 | GFER (0.69) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL11612742 | 0.78 | GFER (0.49) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL1486860 | 0.78 | KDM4E (0.58) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL201539 | 0.78 | GFER (0.72) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL2706140 | 0.78 | GFER (0.72) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL19031390 | 0.78 | GFER (0.72) | GFERALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL2431805 | 0.78 | ALDH1A1 (1.00) | GFERALDH1A1TDP1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586613-B2 | Pyridinium and quinolinium derivatives | UNIVERSIDAD DE GRANADA (ES) | 2013-11-19 | — | — | US | disclosed |
| US-20110178124-A1 | PYRIDINIUM AND QUINOLINIUM DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2011-07-21 | — | — | US | disclosed |
| US-20110178124-A1 | PYRIDINIUM AND QUINOLINIUM DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2011-07-21 | — | — | US | disclosed |
| US-7781458-B2 | Derivatives of pyridine and quinoline | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2010-08-24 | — | — | US | disclosed |
| US-7781458-B2 | Derivatives of pyridine and quinoline | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2010-08-24 | — | — | US | disclosed |
| EP-1710236-B1 | DERIVATIVES OF PYRIDINE AND QUINOLINE | CONSEJO SUPERIOR INVESTIGACION (ES) | 2010-03-24 | — | — | EP | disclosed |
| EP-2085386-A2 | Pyridinium and quinolinium derivatives as Choline kinase inhibitors | Consejo Superior De Investigaciones Científicas (ES) | 2009-08-05 | — | — | EP | disclosed |
| US-20070185170-A1 | Derivatives of pyridine and quinoline | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2007-08-09 | — | — | US | disclosed |
| US-20070185170-A1 | Derivatives of pyridine and quinoline | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2007-08-09 | — | — | US | disclosed |
| EP-1710236-A1 | DERIVATIVES OF PYRIDINE AND QUINOLINE | CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185170-A1 | Derivatives of pyridine and quinoline | CHKA, CHKB, PHOSPHO1 | GFER 4030/4885ALDH1A1 2187/4885TDP1 2645/4885 |
| US-20110178124-A1 | PYRIDINIUM AND QUINOLINIUM DERIVATIVES | CHKA, PHOSPHO1, CHKB | GFER 3927/4885ALDH1A1 2845/4885TDP1 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.