SCHEMBL118764

SCHEMBL118764

ClCc1csc(-c2ccccc2)n1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.71
RAB9A P51151 8/20 0.65
NPC1 O15118 4/20 0.65
GAA P10253 2/20 0.65
POLB P06746 1/20 0.65
TDP1 Q9NUW8 4/20 0.64
ALDH1A1 P00352 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
KDM4E B2RXH2 6/20 0.61
DRD2 P14416 2/20 0.61
DRD4 P21917 2/20 0.61
DRD3 P35462 2/20 0.61
MAPT P10636 5/20 0.59
LMNA P02545 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
HPGD P15428 2/20 0.53
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
ATM Q13315 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28842593 1.00 GFER (0.71) GFERRAB9ANPC1GAAPOLB
Hydrochloric Acid SCHEMBL1715319 0.98 GFER (0.69) GFERRAB9ANPC1GAAPOLB
SCHEMBL5385321 0.85 GFER (0.71) GFERRAB9ANPC1GAAPOLB
SCHEMBL203617 0.83 GFER (1.00) GFERRAB9ANPC1GAAPOLB
SCHEMBL201539 0.81 GFER (0.72) GFERRAB9ANPC1GAAPOLB
SCHEMBL201736 0.81 GFER (0.72) GFERRAB9ANPC1GAAPOLB
SCHEMBL19031390 0.81 GFER (0.72) GFERRAB9ANPC1GAAPOLB
SCHEMBL2706140 0.81 GFER (0.72) GFERRAB9ANPC1GAAPOLB
SCHEMBL19031364 0.81 GFER (0.72) GFERRAB9ANPC1GAAPOLB
SCHEMBL5377137 0.81 CYP19A1 (0.61) GFERRAB9ANPC1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106608873-B Pyrazol acid amide compounds and the preparation method and application thereof 湖南化工研究院有限公司 2019-05-24 CN claimed
CN-109054648-A Serosity combination for chemically mechanical polishing LTCAM有限公司 2018-12-21 CN claimed
CN-106608873-A Pyrazole amide compound, and preparation method and application thereof 湖南化工研究院有限公司 2017-05-03 CN claimed
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
US-12319684-B2 Agonists of the apelin receptor and methods of use thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2025-06-03 US disclosed
US-20240270737-A1 SMALL MOLECULAR INHIBITORS OF STING SIGNALING COMPOSITIONS AND METHODS OF USE STINGINN INC. (US) 2024-08-15 US disclosed
CN-118164881-A Thioamide compound and application thereof 沈阳中化农药化工研发有限公司 2024-06-11 CN disclosed
EP-3661923-B1 N-HETEROCYCLIC COMPOUNDS AS OREXIN 2 AGONISTS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS TAKEDA PHARMACEUTICALS CO (JP) 2024-05-15 EP disclosed
US-11952355-B2 Method of preparing malononitrile oxime ether compound and intermediate compound SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2024-04-09 US disclosed
CN-114276291-B Method for preparing malononitrile oxime ether compound and intermediate compound 沈阳中化农药化工研发有限公司 2023-11-21 CN disclosed
EP-3395795-B1 MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2023-07-19 EP disclosed
CN-113968799-B Malononitrile compound and application thereof 沈阳化工大学 2023-07-04 CN disclosed
US-4703044-A Imidazoquinolines containing other heterocyclic groups, useful as anti-ulcer or anti-secretory agents JOHN WYETH & BROTHER LIMITED (GB) 1987-10-27 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
EP-0146370-A2 Imidazoquinolines containing other heterocyclic groups JOHN WYETH & BROTHER LIMITED (GB) 1985-06-26 EP disclosed
US-4336059-A Herbicidal and plant-growth-regulating N-(heterocyclyl)-methylacetanilide CHEVRON RESEARCH COMPANY (US) 1982-06-22 US disclosed
US-4307105-A FUNGICIDES AND BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1981-12-22 US disclosed
US-4221584-A Herbicidal and plant-growth-regulating N-(heterocyclyl)-methylacetanilides CHEVRON RESEARCH COMPANY (US) 1980-09-09 US disclosed
US-4161571-A GELATION INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-07-17 US disclosed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952355-B2 Method of preparing malononitrile oxime ether compound and intermediate compound CYP2E1, CYP3A4, POR GFER 717/4885RAB9A 3427/4885NPC1 4653/4885
US-20240270737-A1 SMALL MOLECULAR INHIBITORS OF STING SIGNALING COMPOSITIONS AND METHODS OF USE STING1, IRF3, MAVS GFER 4720/4885RAB9A 1949/4885NPC1 2662/4885
US-12319684-B2 Agonists of the apelin receptor and methods of use thereof APLNR, AGTR1, AGTR2 GFER 1608/4885RAB9A 2081/4885NPC1 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.