SCHEMBL31745208

SCHEMBL31745208

CCOC(=O)C(C)(C)Oc1ccc(F)cc1C(O)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 10/20 0.55
▸ PPARA Q07869 2/20 0.42
▸ ABCB11 O95342 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ PMP22 Q01453 1/20 0.42
▸ SCN9A Q15858 1/20 0.38
▸ MGLL Q99685 1/20 0.37
▸ PPARG P37231 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431952 0.80 FBP1 (0.62) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL1417534 0.80 FBP1 (0.62) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL7980993 0.78 FBP1 (0.60) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL7981278 0.78 FBP1 (0.60) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL31745276 0.78 FBP1 (0.57) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL31745150 0.77 FBP1 (0.59) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL2423336 0.77 FBP1 (0.69) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL21188250 0.72 FBP1 (0.53) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL1417870 0.71 PPARA (0.71) FBP1PPARAABCB11CYP1A2CYP3A4
SCHEMBL9234505 0.71 CES2 (0.43) FBP1TSHRMAPTHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667461-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON S AND GAUCHER DISEASE Children's Hospital Medical Center (US) 2025-12-24 — — EP disclosed
US-20250382274-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S AND GAUCHER DISEASE CHILDRENS HOSPITAL MED CT (US) 2025-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382274-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S AND GAUCHER DISEASE GBA1, GAA, GBA2 FBP1 1165/4885PPARA 1402/4885ABCB11 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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