Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | HEXA | P06865 | 2/20 | 0.62 |
| ▸ | HEXB | P07686 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alrestatin SCHEMBL450743 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Alrestatin SCHEMBL636522 | 0.98 | KDM4E (0.97) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11391369 | 0.89 | KDM4E (0.79) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11181448 | 0.88 | KDM4E (0.79) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1413250 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19886995 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30097999 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4582152 | 0.83 | MEN1 (0.82) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL860250 | 0.83 | CA12 (0.70) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29744481 | 0.83 | CA12 (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | ZOUNEK ALEX (DE) | 2025-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | KIT, CTSL, PAICS | KDM4E 2995/4885ALDH1A1 1779/4885HPGD 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.