SCHEMBL4582152

SCHEMBL4582152

O=C(O)CCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.82
KMT2A Q03164 5/20 0.82
KDM4E B2RXH2 7/20 0.71
ALDH1A1 P00352 5/20 0.71
MAPT P10636 3/20 0.71
CYP1A2 P05177 1/20 0.71
AKR1B1 P15121 1/20 0.71
HPGD P15428 1/20 0.71
ALOX15 P16050 1/20 0.71
HSD17B10 Q99714 1/20 0.71
HEXA P06865 6/20 0.68
HEXB P07686 6/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
RAB9A P51151 2/20 0.62
GAA P10253 1/20 0.62
OGA O60502 1/20 0.61
HDAC3 O15379 1/20 0.59
LTA4H P09960 1/20 0.59
HDAC4 P56524 1/20 0.59
HDAC1 Q13547 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134908 0.90 MEN1 (1.00) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL9290373 0.89 MEN1 (0.67) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL10018574 0.88 KMT2A (0.89) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL29297665 0.85 MEN1 (0.66) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL10018578 0.85 MEN1 (0.66) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL3470386 0.85 MEN1 (0.66) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL22473989 0.85 MEN1 (0.62) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL30098360 0.84 CA12 (0.66) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL14023167 0.84 NPSR1 (0.60) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL135305 0.84 CA12 (0.66) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107698648-A Naphthylimide derivative containing cholesterol and synthesis and application thereof 大连理工大学 2018-02-16 CN claimed
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM MC US 3 LLC (US) 2024-07-11 US disclosed
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM MC US 3 LLC (US) 2024-07-11 US disclosed
US-20230183640-A1 METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS LANXESS CORPORATION 2023-06-15 US disclosed
US-20230183640-A1 METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS LANXESS CORPORATION 2023-06-15 US disclosed
CN-115427462-A Fluorescent macromolecules and uses thereof 昆士兰科技大学 2022-12-02 CN disclosed
US-20220252981-A1 HIGHLY SEQUENCED COPOLYMER FOR DUAL-TONE PHOTORESISTS, RESIST COMPOSITION AND PATTERNING PROCESS THEREOF Canton Litho Material Technology Inc. (CN) 2022-08-11 US disclosed
CN-108884638-B Polysaccharide derivatives as optical brighteners 奥布专科学院 2021-08-31 CN disclosed
CN-112876495-A Parthenolide derivative, pharmaceutical composition thereof, preparation method and application thereof 中国医学科学院药物研究所 2021-06-01 CN disclosed
US-10988716-B2 Polysaccharide derivatives as optical brightening agents ABO AKADEMI UNIVERSITY (FI) 2021-04-27 US disclosed
US-20090170840-A1 NS1 protein inhibitors THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-07-02 US disclosed
US-20090170840-A1 NS1 protein inhibitors THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-07-02 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-20080269482-A1 Use of Rylene Derivatives as Photosensitizers in Solar Cells BASF SE (DE) 2008-10-30 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-20040023159-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170840-A1 NS1 protein inhibitors MAVS, SERPINB1, SPINT2 MEN1 3271/4885KMT2A 2284/4885KDM4E 2872/4885
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM RIMKLA, HDHD5, SCD MEN1 4370/4885KMT2A 1215/4885KDM4E 1253/4885
US-10988716-B2 Polysaccharide derivatives as optical brightening agents ALG1, CSGALNACT1, MAN1B1 MEN1 1790/4885KMT2A 3606/4885KDM4E 4447/4885
US-20080269482-A1 Use of Rylene Derivatives as Photosensitizers in Solar Cells NR2E3, NR2E1, NR1D2 MEN1 1376/4885KMT2A 940/4885KDM4E 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.