SCHEMBL31746926

SCHEMBL31746926

N#Cc1cc(Nc2cccc3ccn(CC(=O)NCC(F)(F)F)c(=O)c23)cc2[nH]ncc12

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 18/20 0.39
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DDR2 Q16832 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073892 1.00 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073902 0.89 DDR1 (0.41) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746958 0.89 DDR1 (0.41) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746927 0.88 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073790 0.88 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073848 0.86 DDR1 (0.34) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746893 0.86 DDR1 (0.34) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073910 0.85 DDR1 (0.42) DDR1MAPK1DDR2
SCHEMBL31746900 0.85 DDR1 (0.42) DDR1MAPK1DDR2
SCHEMBL25073851 0.84 KDM4E (0.34) DDR1USP2LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed