SCHEMBL31746958

SCHEMBL31746958

N#Cc1cc(Nc2cccc3ccn(CC(=O)NCC(F)(F)F)c(=O)c23)cc2cn[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 17/20 0.41
MALT1 Q9UDY8 1/20 0.35
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073902 1.00 DDR1 (0.41) DDR1MALT1USP2LMNAMAPK1
SCHEMBL25073865 0.89 DDR1 (0.38) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746963 0.89 DDR1 (0.38) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746926 0.89 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073892 0.89 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073841 0.88 DDR1 (0.39) DDR1USP2LMNAMAPK1HTT
SCHEMBL31746920 0.88 DDR1 (0.43) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073872 0.88 DDR1 (0.43) DDR1USP2LMNAMAPK1HTT
SCHEMBL25073835 0.88 DDR1 (0.40) DDR1
SCHEMBL30279180 0.88 DDR1 (0.40) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed